Sorbinil pharmacokinetics in male and female elderly volunteers.
نویسندگان
چکیده
منابع مشابه
Sorbinil pharmacokinetics in male and female elderly volunteers.
Sorbinil pharmacokinetics were studied, following a single oral dose, in eight male and eight female healthy, elderly volunteers. Elimination half-life tended to be longer in males than in females. There was no sex difference in AUC or renal clearance. The long elimination half-life of sorbinil in the elderly suggests that accumulation is likely to occur with chronic dosing.
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1987
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1987.tb03083.x